Coronavirus News Updates: COVID-19 circumstances in Andhra Pradesh cross 8.81 lakh; vaccine distribution dry run in Krishna district tomorrow

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Coronavirus News Updates: State Health Commissioner Katamaneni Bhaskar mentioned the dry run is geared toward testing the deliberate operations and the laid out mechanisms for COVID-19 vaccination within the state

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Coronavirus News LATEST Updates:   The Andhra Pradesh COVID-19 desk confirmed a complete of 8.81 lakh positives, 8,70,342 recoveries and seven,094 deaths, with 3,625 lively circumstances. The newest well being bulletin mentioned 422 sufferers had recovered from the an infection whereas two extra succumbed in 24 hours.

Meanwhile, state Health Commissioner Katamaneni Bhaskar mentioned the federal government picked Krishna district for a dry run of the coronavirus vaccination programme, including that it will likely be carried out at 5 places within the districts.

On the eve of the three-day session of the Madhya Pradesh Assembly, 61 staff and officers of the Assembly Secretariat and 5 MLAs have examined coronavirus constructive,mentioned Protem Speaker Rameshwar Sharma.

“So far, the test reports of 20 MLAs have been received. The reports of several other legislators are still awaited,” he mentioned.

More than 80 million confirmed circumstances of coronavirus have been detected worldwide for the reason that pandemic started a 12 months in the past and 1.76 million deaths have been registered to this point, based on an AFP tally primarily based on official figures. In complete, 80,145,185 circumstances and 1,756,060 deaths have been recorded. Last week, a mean of 5.80,000 new circumstances have been registered on daily basis. Europe is the world’s hardest-hit area, passing the 25-million-case mark on Friday and with 5,46,000 deaths.

Over 750 volunteers have been administered the primary dose of Bharat Biotech’s COVID-19 vaccine ‘Covaxin’ as a part of its phase-3 trials at Ahmedabad’s Sola Civil Hospital, and none of them have skilled any negative effects to this point , mentioned Dr Kiran Rami, head of the hospital’s TB and chest division.

The Ahmedabad hospital has been chosen for the phase-3 human trials of Covaxin on 1,000 volunteers.

European Union nations formally kicked off a coordinated effort Sunday to present COVID-19 vaccinations to a few of the most weak amongst their practically 450 million individuals, marking a second of hope within the continent’s battle towards the worst public well being disaster in a century.

India’s COVID-19 tally of circumstances climbed to 1,01,87,850 with 18,732 new circumstances in a day, whereas 97,61,538 individuals have recuperated to this point pushing the nationwide restoration fee to 95.82 per cent, based on the Union Health Ministry information up to date on Sunday. This is the bottom every day rely in practically six months, based on NDTV.

Sweden, Canada and Spain on Saturday grew to become the newest nations to report circumstances of the extra contagious and genetically distinct variant of the coronavirus that was first found in Britain. The variant has additionally been detected in France, Denmark, the Netherlands, Germany and Italy, based on The Washington Post.

In the wake of a mutated variant of coronavirus detected within the UK, a genomic surveillance consortium has been shaped for laboratory and epidemiological surveillance of circulating strains of the SARS-CoV-2 in India, the Centre mentioned on Saturday.

The genomic surveillance consortium, INSACOG, has been shaped underneath the management of the National Centre for Disease Control (NCDC), New Delhi. Further, greater than 50 samples of UK returnees are at present underneath sequencing on the designated laboratories.

Five p.c of the constructive circumstances of COVID-19 from all states and UTs shall be examined for Whole Genome Sequencing (WGS) as a part of the technique that has been put in place to detect and comprise the mutant variant, the Union Health Ministry mentioned after a gathering of the National Task Force (NTF) on COVID-19 on the difficulty.

“It is proposed to continue enhanced genomic surveillance for early detection and containment of the UK variant SARS-CoV-2 strains. However, it is important to understand that like all other RNA viruses, SARS-CoV-2 will continue to mutate,” the ministry mentioned.

The mutated virus can be contained by measures like social distancing, hand hygiene, sporting masks and in addition by an efficient vaccine, as and when obtainable, the ministry mentioned.

The assembly of the NTF was convened on Saturday by ICMR underneath co-chairpersonship of Dr Vinod Paul, Member NITI Aayog and Dr Balram Bhargava, Secretary, Director General ICMR.

The most important goal of the assembly was to debate evidence-based modifications in testing, therapy and surveillance methods for SARS-CoV-2 in view of the current experiences of the emergence of a brand new variant pressure of the virus from the UK.

It was emphasised that for the reason that UK variant pressure is implicated to trigger elevated transmissibility of the virus, it’s vital to determine people contaminated with this pressure and adequately comprise them to forestall its transmission in India, the assertion acknowledged.

The NTF concluded that there isn’t any want to alter the prevailing Treatment Protocol in view of mutations rising within the pressure.

Further, since ICMR has all the time advocated using two or extra gene assays for testing SARS-CoV-2, it’s unlikely to overlook contaminated circumstances utilizing the present testing technique, the ministry mentioned.

The NTF beneficial that along with the prevailing surveillance methods, it’s vital to conduct enhanced genomic surveillance for SARS-CoV-2 particularly in incoming passengers from the UK.

The assembly was additionally attended by Prof. Randeep Guleria, Director, AIIMS; Director General Health Services (DGHS); Drug Controller General of India (DCGI); Director, National Center for Disease Control (NCDC); different representatives from Ministry of Health and ICMR in addition to unbiased topic specialists.

“The variant strain has 14 non-synonymous (amino acid altering) mutations, 6 synonymous (non amino-acid altering), and 3 deletions.

“Eight mutations are current within the Spike (S) gene which carries the binding website (Receptor Binding Domain) of the ACE2 receptors, that are the purpose of entry of the virus into the human respiratory cells,” the ministry said in its statement.

The NTF deliberated in detail on aspects related to the current National Treatment Protocol, testing strategy and surveillance of SARS-CoV-2 vis- -vis the UK variant strain.

The NTF was of the view that it will also be critical to conduct genome sequencing in samples where there is a dropout of the S gene in lab diagnosis, proven cases of re-infections etc. Routine genomic surveillance of SARS-CoV-2 from representative samples all across the samples needs to be a continuous and well-planned activity, according to the statement.

The designated laboratories where samples of UK returnees are currently under sequencing include –NCDC, Delhi; CSIR-Institute of Genomics and Integrative Biology, Delhi; CSIR- Centre for Cellular and Molecular Biology, Hyderabad and DBT- Institute of Life Sciences, Bhubaneshwar.

It is also being done at DBT-National Institute of Biomedical Genomics, Kalyani; DBT-InStem-National Centre for Biological Sciences, Bengaluru; National Institute of Mental Health & Neurosciences (NIMHANS), Bengaluru and National Institute of Virology, Pune.

The NCDC informed that the Centre has taken cognizance of the reports of mutant variant and the response of other countries to these reports.

The situation is being monitored proactively.

A strategy has been put under place under which all passengers who had arrived from the UK between December 21n and 23 have been tested at the airports and only after the-PCR test result are available, the negative passengers are permitted to exit the airports

All positively tested passengers are put under institutional isolation and their samples sent for Whole Genome Sequencing (WGS)

Only after the confirmation of the non-mutant variant upon WGS result, the positive cases are permitted to leave institutional isolation as per the existing management protocol

All the contacts of the positive cases are also put under facility quarantine and are tested as per the ICMR guidelines

Besides, the list of all UK arrivals during the last 28 days has been shared by the Bureau of Immigration with the states concerned.

All passengers who had arrived from the UK between 25th November – 20th December 2020 are being tracked by the IDSP State Surveillance Units (SSUs) and District Surveillance Units (DSUs)

Samples of all positive cases are being sent for WGS and enhanced contact tracing of these positive cases is being undertaken and these contacts are also put under facility quarantine.

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